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MDRD study equation was determined by the data for se-rum creatinine values measured by the noncompensated Jaffé method. The abbreviated MDRD study equation modiﬁ ed with the Japanese coefﬁ cient was validated in another set of 269 CKD patients. Results. Indeed, in the Levey study, if for subjects with GFR over 60 ml/min/1.73 m 2, the bias with measured GFR is improved when using the CKD-EPI equations as compared to the MDRD equation (median difference of 3.5 versus 10.6 mL/min/1.73 m 2), however, the precision of the CKD-EPI equation in the same range of GFR doesn't appear better (and even seems slightly worse) than those of the MDRD Glomerular filtration rate (GFR) is the best overall index of kidney function. Normal GFR varies according to age, sex, and body size, and declines with age.

Mdrd study equation

This equation should not be used when eGFR values above 60 mL/min/1.73 m² are desired. GFR (mL/min/1.73 m²) = 175 × (S cr ) -1.154 × (Age) -0.203 × (0.742 if female) × (1.212 if … Noninvasively estimates the measured GFR to determine degree or presence of decreased kidney function. The MDRD equation performs equally to the newer CKD-EPI Equation in patients with GFR of < 60 ml/min/1.73m2. Performs superiorly to the Cockcroft-Gault Equation.

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Am J Kidney. Dis 2009;54:985-6. 32. Stevens LA the CKD Epidemiology Collaboration (CKD-EPI) equation compared with the Modification of Diet in Renal Disease (MDRD) Study equation for estimated GFR. av LC Saiz · 2020 · Citerat av 65 — None of the included studies was blinded to participants or clinicians because of the need to titrate antihypertensives following equation: MBP = [(2 × DBP) + SBP]/3.

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of the MDRD Study Equation for Drug. Dosing', and 'Estimated GFR vs Creatinine. Clearance for Drug Dosing'. Am J Kidney. Dis 2009;54:985-6.

MDRD4: Four-parameter MDRD study equation Description GFR is estimated with the 4-parameter Modification of Diet in Renal Disease (MDRD) study equation. Usage MDRD4(creatinine, sex, age, ethnicity, method = "IDMS") Modification of Diet in Renal Disease Study Group Ann Intern Med 1999 Mar 16; 130 (6): 461-70. A.S. Levey, T. Greene, J.W. Kusek, G.L. Beck, MDRD Study Group.
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The CG equation had the poorest overall accuracy, with the lowest P 10 and a lower P 20 than that of the CKD-EPI equation .

Use of the MDRD Study Equation to Estimate Kidney Function for Drug Dosing. LA Stevens. Corresponding Author. LStevens1@tuftsmedicalcenter.org; Department of Medicine, Tufts Medical Center, Boston, Massachusetts, USA. Search for more papers by this author.
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The CG equation had the poorest overall accuracy, with the lowest P 10 and a lower P 20 than that of the CKD-EPI equation .